Answer:
A symptom is a manifestation of disease apparent to the patient himself, while a sign is a manifestation of disease that the physician perceives.
Explanation:
The key difference between signs and symptoms is who observes the effect. For example, a rash could be a sign, a symptom, or both: If the patient notices the rash, it is a symptom. If the doctor, nurse, or anyone other than the patient notices the rash, it is a sign.
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